4737-7395 Screening compound: 3-(4-chloro-2-methylphenoxy)-4-(3,4-dimethoxyphenyl)-1-[3-(trifluoromethyl)phenyl]azetidin-2-one

4737-7395 Screening compound: 3-(4-chloro-2-methylphenoxy)-4-(3,4-dimethoxyphenyl)-1-[3-(trifluoromethyl)phenyl]azetidin-2-one
4737-7395 Screening compound: 3-(4-chloro-2-methylphenoxy)-4-(3,4-dimethoxyphenyl)-1-[3-(trifluoromethyl)phenyl]azetidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 4737-7395
3-(4-chloro-2-methylphenoxy)-4-(3,4-dimethoxyphenyl)-1-[3-(trifluoromethyl)phenyl]azetidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

4737-7395

Molecular Formula

C25H21ClF3NO4 (C25 H21 ClF3 NO4)

Compound Name

3-(4-chloro-2-methylphenoxy)-4-(3,4-dimethoxyphenyl)-1-[3-(trifluoromethyl)phenyl]azetidin-2-one

IUPAC name

3-(4-chloro-2-methylphenoxy)-4-(34-dimethoxyphenyl)-1-[3-(trifluoromethyl)phenyl]azetidin-2-one

SMILES

Cc(cc(cc1)Cl)c1OC(C(c(cc1)cc(OC)c1OC)N1c2cc(C(F)(F)F)ccc2)C1=O

InChI

InChI=1S/C25H21ClF3NO4/c1-14-11-17(26)8-10-19(14)34-23-22(15-7-9-20(32-2)21(12-15)33-3)30(24(23)31)18-6-4-5-16(13-18)25(27,28)29/h4-13,22-23H,1-3H3

InChI Key

BSTZDIIXUGXFCU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03370954

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

491.89

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.061

Distribution Coefficient, logD

6.061

Water Solubility, LogSw

-6.43

Polar Surface Area

37.137

Acid Dissociation Constant (pKa)

19.36

Base Dissociation Constant (pKb)

-1.49

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

24.00

4737-7395 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 4737-7395 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 4737-7395?
Check Price and Availability of 4737-7395, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 4737-7395 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 4737-7395
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 4737-7395
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 4737-7395 available by request