5142-2672 Screening compound: 3-[4-(dimethylamino)phenyl]-2-(4-methylphenyl)-1,2,3,4-tetrahydroquinazolin-4-one

5142-2672 Screening compound: 3-[4-(dimethylamino)phenyl]-2-(4-methylphenyl)-1,2,3,4-tetrahydroquinazolin-4-one
5142-2672 Screening compound: 3-[4-(dimethylamino)phenyl]-2-(4-methylphenyl)-1,2,3,4-tetrahydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 5142-2672
3-[4-(dimethylamino)phenyl]-2-(4-methylphenyl)-1,2,3,4-tetrahydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5142-2672

Molecular Formula

C23H23N3O (C23 H23 N3 O)

Compound Name

3-[4-(dimethylamino)phenyl]-2-(4-methylphenyl)-1,2,3,4-tetrahydroquinazolin-4-one

IUPAC name

3-[4-(dimethylamino)phenyl]-2-(4-methylphenyl)-1234-tetrahydroquinazolin-4-one

SMILES

Cc1ccc(C(Nc2c3cccc2)N(c(cc2)ccc2N(C)C)C3=O)cc1

InChI

InChI=1S/C23H23N3O/c1-16-8-10-17(11-9-16)22-24-21-7-5-4-6-20(21)23(27)26(22)19-14-12-18(13-15-19)25(2)3/h4-15,22,24H,1-3H3/t22-/m0/s1

InChI Key

GDRTYQKADWYZJQ-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD02234194

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.46

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.837

Distribution Coefficient, logD

4.835

Water Solubility, LogSw

-4.58

Polar Surface Area

29.536

Acid Dissociation Constant (pKa)

13.92

Base Dissociation Constant (pKb)

5.07

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

17.40

5142-2672 in Drug Discovery

Included in Screening Libraries

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 5142-2672 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5142-2672?
Check Price and Availability of 5142-2672, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5142-2672 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5142-2672
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5142-2672
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5142-2672 available by request