5186-0276 Screening compound: N1,N1-diethyl-N4-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]benzene-1,4-diamine

5186-0276 Screening compound: N1,N1-diethyl-N4-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]benzene-1,4-diamine
5186-0276 Screening compound: N1,N1-diethyl-N4-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]benzene-1,4-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound 5186-0276
N1,N1-diethyl-N4-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]benzene-1,4-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5186-0276

Molecular Formula

C20H22FN3S (C20 H22 FN3 S)

Compound Name

N1,N1-diethyl-N4-[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]benzene-1,4-diamine

IUPAC name

N1N1-diethyl-N4-[4-(4-fluoro-3-methylphenyl)-13-thiazol-2-yl]benzene-14-diamine

SMILES

CCN(CC)c(cc1)ccc1Nc1nc(-c(cc2)cc(C)c2F)cs1

InChI

InChI=1S/C20H22FN3S/c1-4-24(5-2)17-9-7-16(8-10-17)22-20-23-19(13-25-20)15-6-11-18(21)14(3)12-15/h6-13H,4-5H2,1-3H3,(H,22,23)

InChI Key

LWYRQRGSLIIBPZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03542519

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

355.48

Hydrogen Bond Acceptors Count

1.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.429

Distribution Coefficient, logD

6.193

Water Solubility, LogSw

-5.90

Polar Surface Area

21.662

Acid Dissociation Constant (pKa)

20.49

Base Dissociation Constant (pKb)

9.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

5186-0276 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with 5186-0276 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5186-0276?
Check Price and Availability of 5186-0276, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5186-0276 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5186-0276
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5186-0276
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5186-0276 available by request