5264-1248 Screening compound: 3-(2-chloro-6-fluorophenyl)-N~4~-(2-methoxydibenzo[b,d]furan-3-yl)-5-methyl-4-isoxazolecarboxamide

5264-1248 Screening compound: 3-(2-chloro-6-fluorophenyl)-N~4~-(2-methoxydibenzo[b,d]furan-3-yl)-5-methyl-4-isoxazolecarboxamide
5264-1248 Screening compound: 3-(2-chloro-6-fluorophenyl)-N~4~-(2-methoxydibenzo[b,d]furan-3-yl)-5-methyl-4-isoxazolecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 5264-1248
3-(2-chloro-6-fluorophenyl)-N~4~-(2-methoxydibenzo[b,d]furan-3-yl)-5-methyl-4-isoxazolecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5264-1248

Molecular Formula

C24H16ClFN2O4 (C24 H16 ClFN2 O4)

Compound Name

3-(2-chloro-6-fluorophenyl)-N~4~-(2-methoxydibenzo[b,d]furan-3-yl)-5-methyl-4-isoxazolecarboxamide

IUPAC name

3-(2-chloro-6-fluorophenyl)-N-{4-methoxy-8-oxatricyclo[7.4.0.0^{27}]trideca-1(9)2(7)351012-hexaen-5-yl}-5-methyl-12-oxazole-4-carboxamide

SMILES

Cc1c(C(Nc(cc2oc(cccc3)c3c2c2)c2OC)=O)c(-c(c(F)ccc2)c2Cl)no1

InChI

InChI=1S/C24H16ClFN2O4/c1-12-21(23(28-32-12)22-15(25)7-5-8-16(22)26)24(29)27-17-11-19-14(10-20(17)30-2)13-6-3-4-9-18(13)31-19/h3-11H,1-2H3,(H,27,29)

InChI Key

UMCSNYPJLBECHE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02220715

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.85

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.674

Distribution Coefficient, logD

5.659

Water Solubility, LogSw

-6.30

Polar Surface Area

60.137

Acid Dissociation Constant (pKa)

8.85

Base Dissociation Constant (pKb)

-0.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

5264-1248 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

GABA Library (7115 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Eye
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Agro:
  • Agro
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with 5264-1248 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5264-1248?
Check Price and Availability of 5264-1248, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5264-1248 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5264-1248
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5264-1248
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5264-1248 available by request