5267-1633 Screening compound: 6-chloro-4-phenyl-3-[(2E)-3-(quinolin-6-yl)prop-2-enoyl]-1,2-dihydroquinolin-2-one

5267-1633 Screening compound: 6-chloro-4-phenyl-3-[(2E)-3-(quinolin-6-yl)prop-2-enoyl]-1,2-dihydroquinolin-2-one
5267-1633 Screening compound: 6-chloro-4-phenyl-3-[(2E)-3-(quinolin-6-yl)prop-2-enoyl]-1,2-dihydroquinolin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 5267-1633
6-chloro-4-phenyl-3-[(2E)-3-(quinolin-6-yl)prop-2-enoyl]-1,2-dihydroquinolin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5267-1633

Molecular Formula

C27H17ClN2O2 (C27 H17 ClN2 O2)

Compound Name

6-chloro-4-phenyl-3-[(2E)-3-(quinolin-6-yl)prop-2-enoyl]-1,2-dihydroquinolin-2-one

IUPAC name

6-chloro-4-phenyl-3-[(2E)-3-(quinolin-6-yl)prop-2-enoyl]-12-dihydroquinolin-2-one

SMILES

O=C(/C=C/c1cc2cccnc2cc1)C1=C(c2ccccc2)c(cc(cc2)Cl)c2NC1=O

InChI

InChI=1S/C27H17ClN2O2/c28-20-10-12-23-21(16-20)25(18-5-2-1-3-6-18)26(27(32)30-23)24(31)13-9-17-8-11-22-19(15-17)7-4-14-29-22/h1-16H,(H,30,32)

InChI Key

FXEHMRFQWCIMSC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00999998

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.9

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.788

Distribution Coefficient, logD

4.773

Water Solubility, LogSw

-6.07

Polar Surface Area

46.583

Acid Dissociation Constant (pKa)

6.43

Base Dissociation Constant (pKb)

2.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

5267-1633 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 5267-1633 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5267-1633?
Check Price and Availability of 5267-1633, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5267-1633 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5267-1633
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5267-1633
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5267-1633 available by request