5275-0056 Screening compound: N-[(5-chloro-8-hydroxyquinolin-7-yl)(thiophen-2-yl)methyl]-2-methylpropanamide

5275-0056 Screening compound: N-[(5-chloro-8-hydroxyquinolin-7-yl)(thiophen-2-yl)methyl]-2-methylpropanamide
5275-0056 Screening compound: N-[(5-chloro-8-hydroxyquinolin-7-yl)(thiophen-2-yl)methyl]-2-methylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 5275-0056
N-[(5-chloro-8-hydroxyquinolin-7-yl)(thiophen-2-yl)methyl]-2-methylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5275-0056

Molecular Formula

C18H17ClN2O2S (C18 H17 ClN2 O2 S)

Compound Name

N-[(5-chloro-8-hydroxyquinolin-7-yl)(thiophen-2-yl)methyl]-2-methylpropanamide

IUPAC name

N-[(5-chloro-8-hydroxyquinolin-7-yl)(thiophen-2-yl)methyl]-2-methylpropanamide

SMILES

CC(C)C(NC(c1cccs1)c(cc(c1cccnc11)Cl)c1O)=O

InChI

InChI=1S/C18H17ClN2O2S/c1-10(2)18(23)21-15(14-6-4-8-24-14)12-9-13(19)11-5-3-7-20-16(11)17(12)22/h3-10,15,22H,1-2H3,(H,21,23)/t15-/m1/s1

InChI Key

MUXXALTZLCUMQQ-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD02732974

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

360.86

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.343

Distribution Coefficient, logD

4.338

Water Solubility, LogSw

-4.30

Polar Surface Area

50.035

Acid Dissociation Constant (pKa)

9.35

Base Dissociation Constant (pKb)

3.91

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.20

5275-0056 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with 5275-0056 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5275-0056?
Check Price and Availability of 5275-0056, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5275-0056 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5275-0056
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5275-0056
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5275-0056 available by request