5340-1219 Screening compound: 4-acetyl-3-hydroxy-5-phenyl-1-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one

5340-1219 Screening compound: 4-acetyl-3-hydroxy-5-phenyl-1-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one
5340-1219 Screening compound: 4-acetyl-3-hydroxy-5-phenyl-1-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 5340-1219
4-acetyl-3-hydroxy-5-phenyl-1-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5340-1219

Molecular Formula

C17H14N2O3 (C17 H14 N2 O3)

Compound Name

4-acetyl-3-hydroxy-5-phenyl-1-(pyridin-2-yl)-2,5-dihydro-1H-pyrrol-2-one

IUPAC name

n/a

SMILES

CC(C(C(c1ccccc1)N(C1=O)c2ncccc2)=C1O)=O

InChI

InChI=1S/C17H14N2O3/c1-11(20)14-15(12-7-3-2-4-8-12)19(17(22)16(14)21)13-9-5-6-10-18-13/h2-10,15,21H,1H3/t15-/m0/s1

InChI Key

VAXODRRSKWXFFS-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD01173729

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

294.31

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.834

Distribution Coefficient, logD

1.803

Water Solubility, LogSw

-1.93

Polar Surface Area

53.086

Acid Dissociation Constant (pKa)

8.53

Base Dissociation Constant (pKb)

-0.36

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

11.80

5340-1219 in Drug Discovery

Included in Screening Libraries

Soluble Diversity Library (15920 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 5340-1219 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5340-1219?
Check Price and Availability of 5340-1219, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5340-1219 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5340-1219
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5340-1219
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5340-1219 available by request