5863-2143 Screening compound: 3'-(3,4-dichlorophenyl)-5'-methyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione

5863-2143 Screening compound: 3'-(3,4-dichlorophenyl)-5'-methyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione
5863-2143 Screening compound: 3'-(3,4-dichlorophenyl)-5'-methyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound 5863-2143
3'-(3,4-dichlorophenyl)-5'-methyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5863-2143

Molecular Formula

C17H12Cl2N2O2S (C17 H12 Cl2 N2 O2 S)

Compound Name

3'-(3,4-dichlorophenyl)-5'-methyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione

IUPAC name

3'-(34-dichlorophenyl)-5'-methyl-12-dihydrospiro[indole-32'-[13]thiazolidine]-24'-dione

SMILES

CC(C1=O)SC(c(cccc2)c2N2)(C2=O)N1c(cc1)cc(Cl)c1Cl

InChI

InChI=1S/C17H12Cl2N2O2S/c1-9-15(22)21(10-6-7-12(18)13(19)8-10)17(24-9)11-4-2-3-5-14(11)20-16(17)23/h2-9H,1H3,(H,20,23)

InChI Key

XUFNHOAVBYEEBT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01423275

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.27

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.353

Distribution Coefficient, logD

4.353

Water Solubility, LogSw

-4.49

Polar Surface Area

40.533

Acid Dissociation Constant (pKa)

10.85

Base Dissociation Constant (pKb)

-2.67

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

17.60

5863-2143 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

BRD4 Targeted Library (4534 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Akt-Targeted Library (14764 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with 5863-2143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5863-2143?
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What is the minimum amount of 5863-2143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5863-2143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5863-2143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5863-2143 available by request