5921-0206 Screening compound: N-[5-(2-furyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-yl]-N-pentylamine

5921-0206 Screening compound: N-[5-(2-furyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-yl]-N-pentylamine
5921-0206 Screening compound: N-[5-(2-furyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-yl]-N-pentylamine alternative view

Chemical Structure Depiction of ChemDiv screening compound 5921-0206
N-[5-(2-furyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-yl]-N-pentylamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

5921-0206

Molecular Formula

C22H24N4OS (C22 H24 N4 OS)

Compound Name

N-[5-(2-furyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-yl]-N-pentylamine

IUPAC name

8-(furan-2-yl)-N-pentyl-11-thia-91416-triazatetracyclo[8.7.0.0^{27}.0^{1217}]heptadeca-1(10)2(7)812(17)1315-hexaen-13-amine

SMILES

CCCCCNc1c2sc3nc(-c4ccco4)c(CCCC4)c4c3c2ncn1

InChI

InChI=1S/C22H24N4OS/c1-2-3-6-11-23-21-20-19(24-13-25-21)17-14-8-4-5-9-15(14)18(26-22(17)28-20)16-10-7-12-27-16/h7,10,12-13H,2-6,8-9,11H2,1H3,(H,23,24,25)

InChI Key

PFWCHBWVCOCWSG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01943445

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.451

Distribution Coefficient, logD

6.450

Water Solubility, LogSw

-6.02

Polar Surface Area

50.239

Acid Dissociation Constant (pKa)

18.55

Base Dissociation Constant (pKb)

4.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

5921-0206 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 5921-0206 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 5921-0206?
Check Price and Availability of 5921-0206, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 5921-0206 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 5921-0206
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 5921-0206
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 5921-0206 available by request