6000-0523 Screening compound: N-(2,4-dimethoxyphenyl)-2-(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetamide

6000-0523 Screening compound: N-(2,4-dimethoxyphenyl)-2-(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetamide
6000-0523 Screening compound: N-(2,4-dimethoxyphenyl)-2-(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 6000-0523
N-(2,4-dimethoxyphenyl)-2-(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6000-0523

Molecular Formula

C18H16N2O5 (C18 H16 N2 O5)

Compound Name

N-(2,4-dimethoxyphenyl)-2-(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetamide

IUPAC name

N-(24-dimethoxyphenyl)-2-(23-dioxo-23-dihydro-1H-indol-1-yl)acetamide

SMILES

COc(cc1)cc(OC)c1NC(CN(c(cccc1)c1C1=O)C1=O)=O

InChI

InChI=1S/C18H16N2O5/c1-24-11-7-8-13(15(9-11)25-2)19-16(21)10-20-14-6-4-3-5-12(14)17(22)18(20)23/h3-9H,10H2,1-2H3,(H,19,21)

InChI Key

JXUOLVPYPQKQCI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04441223

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

340.34

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.795

Distribution Coefficient, logD

1.795

Water Solubility, LogSw

-2.88

Polar Surface Area

66.479

Acid Dissociation Constant (pKa)

11.19

Base Dissociation Constant (pKb)

2.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

6000-0523 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Human Kinases Annotated Library (2415 compounds)

Human Proteases Annotated Library (2868 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 6000-0523 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6000-0523?
Check Price and Availability of 6000-0523, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6000-0523 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6000-0523
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6000-0523
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6000-0523 available by request