6136-0179 Screening compound: 3-phenyl-3-[4-(propan-2-yloxy)phenyl]-N-(1,3-thiazol-2-yl)propanamide

6136-0179 Screening compound: 3-phenyl-3-[4-(propan-2-yloxy)phenyl]-N-(1,3-thiazol-2-yl)propanamide
6136-0179 Screening compound: 3-phenyl-3-[4-(propan-2-yloxy)phenyl]-N-(1,3-thiazol-2-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 6136-0179
3-phenyl-3-[4-(propan-2-yloxy)phenyl]-N-(1,3-thiazol-2-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6136-0179

Molecular Formula

C21H22N2O2S (C21 H22 N2 O2 S)

Compound Name

3-phenyl-3-[4-(propan-2-yloxy)phenyl]-N-(1,3-thiazol-2-yl)propanamide

IUPAC name

3-phenyl-3-[4-(propan-2-yloxy)phenyl]-N-(13-thiazol-2-yl)propanamide

SMILES

CC(C)Oc1ccc(C(CC(Nc2nccs2)=O)c2ccccc2)cc1

InChI

InChI=1S/C21H22N2O2S/c1-15(2)25-18-10-8-17(9-11-18)19(16-6-4-3-5-7-16)14-20(24)23-21-22-12-13-26-21/h3-13,15,19H,14H2,1-2H3,(H,22,23,24)/t19-/m0/s1

InChI Key

WQEZBZVPLHKSKN-IBGZPJMESA-N

MDL Number (MFCD)

MFCD03287514

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.669

Distribution Coefficient, logD

4.659

Water Solubility, LogSw

-4.31

Polar Surface Area

40.126

Acid Dissociation Constant (pKa)

9.03

Base Dissociation Constant (pKb)

0.89

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.80

6136-0179 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Kinases
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 6136-0179 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6136-0179?
Check Price and Availability of 6136-0179, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6136-0179 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6136-0179
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6136-0179
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6136-0179 available by request