6144-0618 Screening compound: quinolin-8-yl 4-(quinoline-8-sulfonamido)benzoate

6144-0618 Screening compound: quinolin-8-yl 4-(quinoline-8-sulfonamido)benzoate
6144-0618 Screening compound: quinolin-8-yl 4-(quinoline-8-sulfonamido)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound 6144-0618
quinolin-8-yl 4-(quinoline-8-sulfonamido)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6144-0618

Molecular Formula

C25H17N3O4S (C25 H17 N3 O4 S)

Compound Name

quinolin-8-yl 4-(quinoline-8-sulfonamido)benzoate

IUPAC name

quinolin-8-yl 4-(quinoline-8-sulfonamido)benzoate

SMILES

O=C(c(cc1)ccc1NS(c1cccc2cccnc12)(=O)=O)Oc1cccc2cccnc12

InChI

InChI=1S/C25H17N3O4S/c29-25(32-21-9-1-5-17-7-3-15-26-23(17)21)19-11-13-20(14-12-19)28-33(30,31)22-10-2-6-18-8-4-16-27-24(18)22/h1-16,28H

InChI Key

YONOGJAXRFKJHT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08161442

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.49

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.682

Distribution Coefficient, logD

2.472

Water Solubility, LogSw

-3.81

Polar Surface Area

80.419

Acid Dissociation Constant (pKa)

6.22

Base Dissociation Constant (pKb)

4.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

6144-0618 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SH2 Library (10483 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 6144-0618 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6144-0618?
Check Price and Availability of 6144-0618, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6144-0618 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6144-0618
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6144-0618
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6144-0618 available by request