6173-0277 Screening compound: N-(4-fluorophenyl)-2-{[(4-methoxyphenyl)methyl]amino}-4-oxo-5,6-dihydro-4H-1,3-thiazine-6-carboxamide

6173-0277 Screening compound: N-(4-fluorophenyl)-2-{[(4-methoxyphenyl)methyl]amino}-4-oxo-5,6-dihydro-4H-1,3-thiazine-6-carboxamide
6173-0277 Screening compound: N-(4-fluorophenyl)-2-{[(4-methoxyphenyl)methyl]amino}-4-oxo-5,6-dihydro-4H-1,3-thiazine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 6173-0277
N-(4-fluorophenyl)-2-{[(4-methoxyphenyl)methyl]amino}-4-oxo-5,6-dihydro-4H-1,3-thiazine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6173-0277

Molecular Formula

C19H18FN3O3S (C19 H18 FN3 O3 S)

Compound Name

N-(4-fluorophenyl)-2-{[(4-methoxyphenyl)methyl]amino}-4-oxo-5,6-dihydro-4H-1,3-thiazine-6-carboxamide

IUPAC name

N-(4-fluorophenyl)-2-{[(4-methoxyphenyl)methyl]amino}-4-oxo-56-dihydro-4H-13-thiazine-6-carboxamide

SMILES

COc1ccc(CNC(SC(C2)C(Nc(cc3)ccc3F)=O)=NC2=O)cc1

InChI

InChI=1S/C19H18FN3O3S/c1-26-15-8-2-12(3-9-15)11-21-19-23-17(24)10-16(27-19)18(25)22-14-6-4-13(20)5-7-14/h2-9,16H,10-11H2,1H3,(H,22,25)(H,21,23,24)/t16-/m0/s1

InChI Key

UZFLDMDDNJKAGZ-INIZCTEOSA-N

MDL Number (MFCD)

MFCD03941407

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.346

Distribution Coefficient, logD

2.346

Water Solubility, LogSw

-2.92

Polar Surface Area

63.430

Acid Dissociation Constant (pKa)

10.61

Base Dissociation Constant (pKb)

1.53

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

21.10

6173-0277 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

C-Met Library (15277 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 6173-0277 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6173-0277?
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What is the minimum amount of 6173-0277 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6173-0277
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6173-0277
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6173-0277 available by request