6264-0351 Screening compound: methyl 2-[7-bromo-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-1-yl]acetate

Chemical Structure Depiction of ChemDiv screening compound 6264-0351
methyl 2-[7-bromo-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-1-yl]acetate

Available from 1 mg

Formats:

Glass Vials (4ml Glass Vials VWR #97047-678)
96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

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Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6264-0351

Molecular Formula

C₁₈H₁₄BrClN₂O₃ (C18 H14 BrClN2 O3)

Compound Name

methyl 2-[7-bromo-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-1-yl]acetate

IUPAC name

methyl 2-[7-bromo-5-(2-chlorophenyl)-2-oxo-23-dihydro-1H-14-benzodiazepin-1-yl]acetate

SMILES

COC(CN(c(ccc(Br)c1)c1C(c(cccc1)c1Cl)=NC1)C1=O)=O

InChI

InChI=1S/C18H14BrClN2O3/c1-25-17(24)10-22-15-7-6-11(19)8-13(15)18(21-9-16(22)23)12-4-2-3-5-14(12)20/h2-8H,9-10H2,1H3

InChI Key

RXYBIZPPDUOOGI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04026388

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.68

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

Partition Coefficient, logP

2.839

Distribution Coefficient, logD

2.839

Water Solubility, LogSw

-3.61

Polar Surface Area

44.792

Acid Dissociation Constant (pK_a)

21.86

Base Dissociation Constant (pK_b)

0.11

Number of Chiral Centers

0.00

Percent sp³ carbon bonding

16.70

6264-0351 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-Aging Library (44940 compounds)

Antiparasite Library (23996 compounds)

Antiviral Library (67538 compounds)

Dark Chemical Matter Library (18430 compounds)

GABA Library (7115 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epigenetics Focused Set (26518 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:

3D
Pool

Therapeutical areas:

Cancer
Female
Congenital
Skin
Cancer
Musculoskeletal
Metabolic
Immune system
Infections
Immune system
animal
Antiviral
Infections
Immune system
Eye
Cancer
Musculoskeletal
Digestive system
Respiratory tract
Male
Female
Hemic and lymphatic
Metabolic

Targets:

Kinases
GPCR
Ion Channels
Others

Mechanism of action:

Epigenetic
Receptor's ligands
Epigenetic

Agro:

Agro

References: we are preparing a list of scientific research reports with 6264-0351 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6264-0351?
Check Price and Availability of 6264-0351, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.

What is the minimum amount of 6264-0351 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.

Delivery options for 6264-0351
ChemDiv sends parcels with Express services (UPS, WC).

1–2 days for small orders
2–4 weeks for large selections

Delivery formats for 6264-0351

0.5–50 mg of dry powder sample in single glass vials, custom vials
DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6264-0351 available by request