6290-0154 Screening compound: 2-oxo-2-(10H-phenothiazin-10-yl)ethyl 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetate

6290-0154 Screening compound: 2-oxo-2-(10H-phenothiazin-10-yl)ethyl 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetate
6290-0154 Screening compound: 2-oxo-2-(10H-phenothiazin-10-yl)ethyl 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound 6290-0154
2-oxo-2-(10H-phenothiazin-10-yl)ethyl 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6290-0154

Molecular Formula

C22H19N3O3S2 (C22 H19 N3 O3 S2)

Compound Name

2-oxo-2-(10H-phenothiazin-10-yl)ethyl 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetate

IUPAC name

2-oxo-2-(10H-phenothiazin-10-yl)ethyl 2-[(46-dimethylpyrimidin-2-yl)sulfanyl]acetate

SMILES

Cc1nc(SCC(OCC(N2c(cccc3)c3Sc3c2cccc3)=O)=O)nc(C)c1

InChI

InChI=1S/C22H19N3O3S2/c1-14-11-15(2)24-22(23-14)29-13-21(27)28-12-20(26)25-16-7-3-5-9-18(16)30-19-10-6-4-8-17(19)25/h3-11H,12-13H2,1-2H3

InChI Key

GRZXZMDMXIISII-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04128660

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.54

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.821

Distribution Coefficient, logD

3.821

Water Solubility, LogSw

-3.91

Polar Surface Area

50.783

Acid Dissociation Constant (pKa)

16.87

Base Dissociation Constant (pKb)

3.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

6290-0154 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with 6290-0154 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6290-0154?
Check Price and Availability of 6290-0154, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6290-0154 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6290-0154
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6290-0154
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6290-0154 available by request