6574-0146 Screening compound: N-[5-(4-chlorophenyl)-1,2,4-thiadiazol-3-yl]-2-(quinolin-2-ylsulfanyl)acetamide

6574-0146 Screening compound: N-[5-(4-chlorophenyl)-1,2,4-thiadiazol-3-yl]-2-(quinolin-2-ylsulfanyl)acetamide
6574-0146 Screening compound: N-[5-(4-chlorophenyl)-1,2,4-thiadiazol-3-yl]-2-(quinolin-2-ylsulfanyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 6574-0146
N-[5-(4-chlorophenyl)-1,2,4-thiadiazol-3-yl]-2-(quinolin-2-ylsulfanyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6574-0146

Molecular Formula

C19H13ClN4OS2 (C19 H13 ClN4 OS2)

Compound Name

N-[5-(4-chlorophenyl)-1,2,4-thiadiazol-3-yl]-2-(quinolin-2-ylsulfanyl)acetamide

IUPAC name

N-[5-(4-chlorophenyl)-124-thiadiazol-3-yl]-2-(quinolin-2-ylsulfanyl)acetamide

SMILES

O=C(CSc1nc2ccccc2cc1)Nc1nsc(-c(cc2)ccc2Cl)n1

InChI

InChI=1S/C19H13ClN4OS2/c20-14-8-5-13(6-9-14)18-23-19(24-27-18)22-16(25)11-26-17-10-7-12-3-1-2-4-15(12)21-17/h1-10H,11H2,(H,22,24,25)

InChI Key

OSIZEGISBQWQSO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04000909

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.92

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.403

Distribution Coefficient, logD

5.403

Water Solubility, LogSw

-6.37

Polar Surface Area

52.489

Acid Dissociation Constant (pKa)

11.45

Base Dissociation Constant (pKb)

1.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

6574-0146 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Human Phosphatases Annotated Library (206 compounds)

Human Receptors Annotated Library (5376 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

New Agro Library (44492 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Agro:
  • Agro
Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with 6574-0146 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6574-0146?
Check Price and Availability of 6574-0146, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 6574-0146 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6574-0146
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6574-0146
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6574-0146 available by request