6703-2477 Screening compound: 7-(4-pyridyl)-7,14-dihydro-6H-benzo[f]chromeno[4,3-b]quinolin-6-one

6703-2477 Screening compound: 7-(4-pyridyl)-7,14-dihydro-6H-benzo[f]chromeno[4,3-b]quinolin-6-one
6703-2477 Screening compound: 7-(4-pyridyl)-7,14-dihydro-6H-benzo[f]chromeno[4,3-b]quinolin-6-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 6703-2477
7-(4-pyridyl)-7,14-dihydro-6H-benzo[f]chromeno[4,3-b]quinolin-6-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6703-2477

Molecular Formula

C25H16N2O2 (C25 H16 N2 O2)

Compound Name

7-(4-pyridyl)-7,14-dihydro-6H-benzo[f]chromeno[4,3-b]quinolin-6-one

IUPAC name

13-(pyridin-4-yl)-10-oxa-2-azapentacyclo[12.8.0.0^{312}.0^{49}.0^{1520}]docosa-1(22)3(12)4(9)5714161820-nonaen-11-one

SMILES

O=C1Oc(cccc2)c2C2=C1C(c1ccncc1)c(c1ccccc1cc1)c1N2

InChI

InChI=1S/C25H16N2O2/c28-25-23-21(16-11-13-26-14-12-16)22-17-6-2-1-5-15(17)9-10-19(22)27-24(23)18-7-3-4-8-20(18)29-25/h1-14,21,27H/t21-/m0/s1

InChI Key

OTPDUIMBFVVOKJ-NRFANRHFSA-N

MDL Number (MFCD)

MFCD05987876

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.41

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.580

Distribution Coefficient, logD

4.563

Water Solubility, LogSw

-4.91

Polar Surface Area

41.066

Acid Dissociation Constant (pKa)

8.81

Base Dissociation Constant (pKb)

2.29

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

4.00

6703-2477 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 6703-2477 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6703-2477?
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What is the minimum amount of 6703-2477 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6703-2477
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6703-2477
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6703-2477 available by request