6810-0141 Screening compound: 5-amino-8-(4-chlorophenyl)-11,11-dimethyl-9-oxo-8H,9H,10H,11H,12H-quinolino[1,2-a]quinazoline-7-carbonitrile

6810-0141 Screening compound: 5-amino-8-(4-chlorophenyl)-11,11-dimethyl-9-oxo-8H,9H,10H,11H,12H-quinolino[1,2-a]quinazoline-7-carbonitrile
6810-0141 Screening compound: 5-amino-8-(4-chlorophenyl)-11,11-dimethyl-9-oxo-8H,9H,10H,11H,12H-quinolino[1,2-a]quinazoline-7-carbonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound 6810-0141
5-amino-8-(4-chlorophenyl)-11,11-dimethyl-9-oxo-8H,9H,10H,11H,12H-quinolino[1,2-a]quinazoline-7-carbonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

6810-0141

Molecular Formula

C25H21ClN4O (C25 H21 ClN4 O)

Compound Name

5-amino-8-(4-chlorophenyl)-11,11-dimethyl-9-oxo-8H,9H,10H,11H,12H-quinolino[1,2-a]quinazoline-7-carbonitrile

IUPAC name

5-amino-8-(4-chlorophenyl)-1111-dimethyl-9-oxo-8H9H10H11H12H-quinolino[12-a]quinazoline-7-carbonitrile

SMILES

CC(C)(C1)CC(N(c(cccc2)c2C(N)=N2)C2=C(C2c(cc3)ccc3Cl)C#N)=C2C1=O

InChI

InChI=1S/C25H21ClN4O/c1-25(2)11-19-22(20(31)12-25)21(14-7-9-15(26)10-8-14)17(13-27)24-29-23(28)16-5-3-4-6-18(16)30(19)24/h3-10,21H,11-12H2,1-2H3,(H2,28,29)/t21-/m1/s1

InChI Key

VNTZJRCGIQLNFC-OAQYLSRUSA-N

MDL Number (MFCD)

MFCD14712078

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.92

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.001

Distribution Coefficient, logD

-1.402

Water Solubility, LogSw

-4.99

Polar Surface Area

60.666

Acid Dissociation Constant (pKa)

14.67

Base Dissociation Constant (pKb)

12.80

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

24.00

6810-0141 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Selective Target Activity Profiling Library (14702 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Nervous system
Targets:
  • Kinases
  • Others
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with 6810-0141 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 6810-0141?
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What is the minimum amount of 6810-0141 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 6810-0141
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 6810-0141
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 6810-0141 available by request