8002-6623 Screening compound: N-(2-{2-[(E)-1-(4-hydroxy-3-methoxyphenyl)methylidene]hydrazino}-2-oxoethyl)-2-furamide

8002-6623 Screening compound: N-(2-{2-[(E)-1-(4-hydroxy-3-methoxyphenyl)methylidene]hydrazino}-2-oxoethyl)-2-furamide
8002-6623 Screening compound: N-(2-{2-[(E)-1-(4-hydroxy-3-methoxyphenyl)methylidene]hydrazino}-2-oxoethyl)-2-furamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8002-6623
N-(2-{2-[(E)-1-(4-hydroxy-3-methoxyphenyl)methylidene]hydrazino}-2-oxoethyl)-2-furamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8002-6623

Molecular Formula

C15H15N3O5 (C15 H15 N3 O5)

Compound Name

N-(2-{2-[(E)-1-(4-hydroxy-3-methoxyphenyl)methylidene]hydrazino}-2-oxoethyl)-2-furamide

IUPAC name

N-({N'-[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]hydrazinecarbonyl}methyl)furan-2-carboxamide

SMILES

COc(cc(/C=N/NC(CNC(c1ccco1)=O)=O)cc1)c1O

InChI

InChI=1S/C15H15N3O5/c1-22-13-7-10(4-5-11(13)19)8-17-18-14(20)9-16-15(21)12-3-2-6-23-12/h2-8,19H,9H2,1H3,(H,16,21)(H,18,20)

InChI Key

YYAXDFBWJXLXOZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00733146

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

317.3

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.930

Distribution Coefficient, logD

0.927

Water Solubility, LogSw

-1.79

Polar Surface Area

92.783

Acid Dissociation Constant (pKa)

9.56

Base Dissociation Constant (pKb)

0.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.33

8002-6623 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

Carbonic Anhydrase II Library (4939 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8002-6623 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8002-6623?
Check Price and Availability of 8002-6623, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8002-6623 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8002-6623
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8002-6623
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8002-6623 available by request