8003-1528 Screening compound: 4-bromo-2-[(E)-[(2-hydroxy-2,2-diphenylacetamido)imino]methyl]phenyl furan-2-carboxylate

8003-1528 Screening compound: 4-bromo-2-[(E)-[(2-hydroxy-2,2-diphenylacetamido)imino]methyl]phenyl furan-2-carboxylate
8003-1528 Screening compound: 4-bromo-2-[(E)-[(2-hydroxy-2,2-diphenylacetamido)imino]methyl]phenyl furan-2-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound 8003-1528
4-bromo-2-[(E)-[(2-hydroxy-2,2-diphenylacetamido)imino]methyl]phenyl furan-2-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8003-1528

Molecular Formula

C26H19BrN2O5 (C26 H19 BrN2 O5)

Compound Name

4-bromo-2-[(E)-[(2-hydroxy-2,2-diphenylacetamido)imino]methyl]phenyl furan-2-carboxylate

IUPAC name

4-bromo-2-[(E)-[(2-hydroxy-22-diphenylacetamido)imino]methyl]phenyl furan-2-carboxylate

SMILES

OC(C(N/N=C/c(cc(cc1)Br)c1OC(c1ccco1)=O)=O)(c1ccccc1)c1ccccc1

InChI

InChI=1S/C26H19BrN2O5/c27-21-13-14-22(34-24(30)23-12-7-15-33-23)18(16-21)17-28-29-25(31)26(32,19-8-3-1-4-9-19)20-10-5-2-6-11-20/h1-17,32H,(H,29,31)

InChI Key

RBNDGHNZIYULJC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00734255

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

519.35

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.800

Distribution Coefficient, logD

4.689

Water Solubility, LogSw

-4.69

Polar Surface Area

79.394

Acid Dissociation Constant (pKa)

7.93

Base Dissociation Constant (pKb)

-2.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

3.80

8003-1528 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8003-1528 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8003-1528?
Check Price and Availability of 8003-1528, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8003-1528 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8003-1528
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8003-1528
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8003-1528 available by request