8004-4289 Screening compound: N'-[(E)-(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-2-[(naphthalen-2-yl)amino]acetohydrazide

8004-4289 Screening compound: N'-[(E)-(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-2-[(naphthalen-2-yl)amino]acetohydrazide
8004-4289 Screening compound: N'-[(E)-(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-2-[(naphthalen-2-yl)amino]acetohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8004-4289
N'-[(E)-(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-2-[(naphthalen-2-yl)amino]acetohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8004-4289

Molecular Formula

C21H21N3O4 (C21 H21 N3 O4)

Compound Name

N'-[(E)-(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-2-[(naphthalen-2-yl)amino]acetohydrazide

IUPAC name

N'-[(E)-(4-hydroxy-35-dimethoxyphenyl)methylidene]-2-[(naphthalen-2-yl)amino]acetohydrazide

SMILES

COc1cc(/C=N/NC(CNc2cc3ccccc3cc2)=O)cc(OC)c1O

InChI

InChI=1S/C21H21N3O4/c1-27-18-9-14(10-19(28-2)21(18)26)12-23-24-20(25)13-22-17-8-7-15-5-3-4-6-16(15)11-17/h3-12,22,26H,13H2,1-2H3,(H,24,25)

InChI Key

AJPJRIVPOCPQEL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00745740

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.42

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.305

Distribution Coefficient, logD

3.299

Water Solubility, LogSw

-3.59

Polar Surface Area

76.315

Acid Dissociation Constant (pKa)

9.24

Base Dissociation Constant (pKb)

2.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

8004-4289 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8004-4289 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8004-4289?
Check Price and Availability of 8004-4289, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8004-4289 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8004-4289
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8004-4289
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8004-4289 available by request