8005-0294 Screening compound: 2-[(Z)-{[4-(4-chlorophenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]imino}methyl]-6-methoxyphenol

8005-0294 Screening compound: 2-[(Z)-{[4-(4-chlorophenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]imino}methyl]-6-methoxyphenol
8005-0294 Screening compound: 2-[(Z)-{[4-(4-chlorophenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]imino}methyl]-6-methoxyphenol alternative view

Chemical Structure Depiction of ChemDiv screening compound 8005-0294
2-[(Z)-{[4-(4-chlorophenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]imino}methyl]-6-methoxyphenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8005-0294

Molecular Formula

C23H16ClN3O4S (C23 H16 ClN3 O4 S)

Compound Name

2-[(Z)-{[4-(4-chlorophenyl)-5-(4-nitrophenyl)-1,3-thiazol-2-yl]imino}methyl]-6-methoxyphenol

IUPAC name

2-[(Z)-{[4-(4-chlorophenyl)-5-(4-nitrophenyl)-13-thiazol-2-yl]imino}methyl]-6-methoxyphenol

SMILES

COc1cccc(/C=N\c2nc(-c(cc3)ccc3Cl)c(-c(cc3)ccc3[N+]([O-])=O)s2)c1O

InChI

InChI=1S/C23H16ClN3O4S/c1-31-19-4-2-3-16(21(19)28)13-25-23-26-20(14-5-9-17(24)10-6-14)22(32-23)15-7-11-18(12-8-15)27(29)30/h2-13,28H,1H3

InChI Key

IENKVNMWYVJAGW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00747116

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.92

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.660

Distribution Coefficient, logD

6.655

Water Solubility, LogSw

-6.35

Polar Surface Area

75.131

Acid Dissociation Constant (pKa)

9.48

Base Dissociation Constant (pKb)

4.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.35

8005-0294 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with 8005-0294 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8005-0294?
Check Price and Availability of 8005-0294, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8005-0294 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8005-0294
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8005-0294
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8005-0294 available by request