8005-0723 Screening compound: 2-(4-bromonaphthalen-1-yl)-N'-[(E)-(3,4-dimethoxyphenyl)methylidene]acetohydrazide

8005-0723 Screening compound: 2-(4-bromonaphthalen-1-yl)-N'-[(E)-(3,4-dimethoxyphenyl)methylidene]acetohydrazide
8005-0723 Screening compound: 2-(4-bromonaphthalen-1-yl)-N'-[(E)-(3,4-dimethoxyphenyl)methylidene]acetohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8005-0723
2-(4-bromonaphthalen-1-yl)-N'-[(E)-(3,4-dimethoxyphenyl)methylidene]acetohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8005-0723

Molecular Formula

C21H19BrN2O3 (C21 H19 BrN2 O3)

Compound Name

2-(4-bromonaphthalen-1-yl)-N'-[(E)-(3,4-dimethoxyphenyl)methylidene]acetohydrazide

IUPAC name

2-(4-bromonaphthalen-1-yl)-N'-[(E)-(34-dimethoxyphenyl)methylidene]acetohydrazide

SMILES

COc(ccc(/C=N/NC(Cc(c1ccccc11)ccc1Br)=O)c1)c1OC

InChI

InChI=1S/C21H19BrN2O3/c1-26-19-10-7-14(11-20(19)27-2)13-23-24-21(25)12-15-8-9-18(22)17-6-4-3-5-16(15)17/h3-11,13H,12H2,1-2H3,(H,24,25)

InChI Key

YXIBQRMEPRRSFR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00747285

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.3

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.613

Distribution Coefficient, logD

4.613

Water Solubility, LogSw

-4.52

Polar Surface Area

50.330

Acid Dissociation Constant (pKa)

10.29

Base Dissociation Constant (pKb)

2.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

8005-0723 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with 8005-0723 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8005-0723?
Check Price and Availability of 8005-0723, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8005-0723 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8005-0723
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8005-0723
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8005-0723 available by request