8006-6408 Screening compound: 2-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-1,3-benzodiazol-1-yl]-N'-[(E)-{4-[(2,4-dichlorophenyl)methoxy]-3-methoxyphenyl}methylidene]acetohydrazide

8006-6408 Screening compound: 2-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-1,3-benzodiazol-1-yl]-N'-[(E)-{4-[(2,4-dichlorophenyl)methoxy]-3-methoxyphenyl}methylidene]acetohydrazide
8006-6408 Screening compound: 2-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-1,3-benzodiazol-1-yl]-N'-[(E)-{4-[(2,4-dichlorophenyl)methoxy]-3-methoxyphenyl}methylidene]acetohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8006-6408
2-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-1,3-benzodiazol-1-yl]-N'-[(E)-{4-[(2,4-dichlorophenyl)methoxy]-3-methoxyphenyl}methylidene]acetohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8006-6408

Molecular Formula

C26H21Cl2N7O4 (C26 H21 Cl2 N7 O4)

Compound Name

2-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1H-1,3-benzodiazol-1-yl]-N'-[(E)-{4-[(2,4-dichlorophenyl)methoxy]-3-methoxyphenyl}methylidene]acetohydrazide

IUPAC name

2-[2-(4-amino-125-oxadiazol-3-yl)-1H-13-benzodiazol-1-yl]-N'-[(E)-{4-[(24-dichlorophenyl)methoxy]-3-methoxyphenyl}methylidene]acetohydrazide

SMILES

COc(cc(/C=N/NC(Cn1c(-c2nonc2N)nc2c1cccc2)=O)cc1)c1OCc(ccc(Cl)c1)c1Cl

InChI

InChI=1S/C26H21Cl2N7O4/c1-37-22-10-15(6-9-21(22)38-14-16-7-8-17(27)11-18(16)28)12-30-32-23(36)13-35-20-5-3-2-4-19(20)31-26(35)24-25(29)34-39-33-24/h2-12H,13-14H2,1H3,(H2,29,34)(H,32,36)

InChI Key

MPSYHNLBAHJSCA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00825944

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

566.4

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

5.284

Distribution Coefficient, logD

5.283

Water Solubility, LogSw

-5.96

Polar Surface Area

117.299

Acid Dissociation Constant (pKa)

10.63

Base Dissociation Constant (pKb)

4.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.50

8006-6408 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8006-6408 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8006-6408?
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What is the minimum amount of 8006-6408 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8006-6408
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8006-6408
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8006-6408 available by request