8008-5266 Screening compound: 2-{4-[(3-{[4-(5-carboxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-2-chloroanilino]carbonyl}benzoyl)amino]-3-chlorophenyl}-1,3-dioxo-5-isoindolinecarboxylic acid

8008-5266 Screening compound: 2-{4-[(3-{[4-(5-carboxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-2-chloroanilino]carbonyl}benzoyl)amino]-3-chlorophenyl}-1,3-dioxo-5-isoindolinecarboxylic acid
8008-5266 Screening compound: 2-{4-[(3-{[4-(5-carboxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-2-chloroanilino]carbonyl}benzoyl)amino]-3-chlorophenyl}-1,3-dioxo-5-isoindolinecarboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound 8008-5266
2-{4-[(3-{[4-(5-carboxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-2-chloroanilino]carbonyl}benzoyl)amino]-3-chlorophenyl}-1,3-dioxo-5-isoindolinecarboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8008-5266

Molecular Formula

C38H20Cl2N4O10 (C38 H20 Cl2 N4 O10)

Compound Name

2-{4-[(3-{[4-(5-carboxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-2-chloroanilino]carbonyl}benzoyl)amino]-3-chlorophenyl}-1,3-dioxo-5-isoindolinecarboxylic acid

IUPAC name

2-[4-(3-{[4-(5-carboxy-13-dioxo-23-dihydro-1H-isoindol-2-yl)-2-chlorophenyl]carbamoyl}benzamido)-3-chlorophenyl]-13-dioxo-23-dihydro-1H-isoindole-5-carboxylic acid

SMILES

OC(c(cc1)cc(C(N2c(cc3)cc(Cl)c3NC(c3cccc(C(Nc(ccc(N(C(c(cc4)c5cc4C(O)=O)=O)C5=O)c4)c4Cl)=O)c3)=O)=O)c1C2=O)=O

InChI

InChI=1S/C38H20Cl2N4O10/c39-27-15-21(43-33(47)23-8-4-19(37(51)52)13-25(23)35(43)49)6-10-29(27)41-31(45)17-2-1-3-18(12-17)32(46)42-30-11-7-22(16-28(30)40)44-34(48)24-9-5-20(38(53)54)14-26(24)36(44)50/h1-16H,(H,41,45)(H,42,46)(H,51,52)(H,53,54)

InChI Key

VRWDSKWWXPDKEY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01131728

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

763.5

Hydrogen Bond Acceptors Count

18.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

14

Partition Coefficient, logP

6.369

Distribution Coefficient, logD

2.391

Water Solubility, LogSw

-5.96

Polar Surface Area

159.124

Acid Dissociation Constant (pKa)

3.42

Base Dissociation Constant (pKb)

-3.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

8008-5266 in Drug Discovery

Included in Screening Libraries

Regenerative Medicine Focused Library (23016 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with 8008-5266 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8008-5266?
Check Price and Availability of 8008-5266, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8008-5266 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8008-5266
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8008-5266
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8008-5266 available by request