8008-9768 Screening compound: N'1,N'3-bis[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]-2,4-diphenylcyclobutane-1,3-dicarbohydrazide

8008-9768 Screening compound: N'1,N'3-bis[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]-2,4-diphenylcyclobutane-1,3-dicarbohydrazide
8008-9768 Screening compound: N'1,N'3-bis[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]-2,4-diphenylcyclobutane-1,3-dicarbohydrazide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8008-9768
N'1,N'3-bis[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]-2,4-diphenylcyclobutane-1,3-dicarbohydrazide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8008-9768

Molecular Formula

C34H32N4O6 (C34 H32 N4 O6)

Compound Name

N'1,N'3-bis[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]-2,4-diphenylcyclobutane-1,3-dicarbohydrazide

IUPAC name

N'1N'3-bis[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]-24-diphenylcyclobutane-13-dicarbohydrazide

SMILES

COc(cc(/C=N/NC(C(C(C1C(N/N=C/c(cc2)cc(OC)c2O)=O)c2ccccc2)C1c1ccccc1)=O)cc1)c1O

InChI

InChI=1S/C34H32N4O6/c1-43-27-17-21(13-15-25(27)39)19-35-37-33(41)31-29(23-9-5-3-6-10-23)32(30(31)24-11-7-4-8-12-24)34(42)38-36-20-22-14-16-26(40)28(18-22)44-2/h3-20,29-32,39-40H,1-2H3,(H,37,41)(H,38,42)

InChI Key

WKRIHBSLOYQCOW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01061574

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

592.65

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

4.820

Distribution Coefficient, logD

4.618

Water Solubility, LogSw

-4.36

Polar Surface Area

119.207

Acid Dissociation Constant (pKa)

7.63

Base Dissociation Constant (pKb)

0.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.60

8008-9768 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8008-9768 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8008-9768?
Check Price and Availability of 8008-9768, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8008-9768 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8008-9768
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8008-9768
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8008-9768 available by request