8009-2141 Screening compound: 1-{1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine

8009-2141 Screening compound: 1-{1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine
8009-2141 Screening compound: 1-{1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8009-2141
1-{1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8009-2141

Molecular Formula

C24H24N6 (C24 H24 N6)

Compound Name

1-{1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine

IUPAC name

1-{1-phenyl-1H-pyrazolo[34-d]pyrimidin-4-yl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine

SMILES

C(/C=C/c1ccccc1)N(CC1)CCN1c1ncnc2c1cnn2-c1ccccc1

InChI

InChI=1S/C24H24N6/c1-3-8-20(9-4-1)10-7-13-28-14-16-29(17-15-28)23-22-18-27-30(24(22)26-19-25-23)21-11-5-2-6-12-21/h1-12,18-19H,13-17H2

InChI Key

KDHZTZSKBYULCZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00612548

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

396.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.751

Distribution Coefficient, logD

4.742

Water Solubility, LogSw

-4.67

Polar Surface Area

41.380

Acid Dissociation Constant (pKa)

21.11

Base Dissociation Constant (pKb)

5.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

8009-2141 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8009-2141 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8009-2141?
Check Price and Availability of 8009-2141, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8009-2141 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8009-2141
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8009-2141
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8009-2141 available by request