8009-6349 Screening compound: 4,4,8-trimethyl-2-[4-(trifluoromethyl)phenyl]-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione

8009-6349 Screening compound: 4,4,8-trimethyl-2-[4-(trifluoromethyl)phenyl]-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione
8009-6349 Screening compound: 4,4,8-trimethyl-2-[4-(trifluoromethyl)phenyl]-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione alternative view

Chemical Structure Depiction of ChemDiv screening compound 8009-6349
4,4,8-trimethyl-2-[4-(trifluoromethyl)phenyl]-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8009-6349

Molecular Formula

C20H17F3N2S2 (C20 H17 F3 N2 S2)

Compound Name

4,4,8-trimethyl-2-[4-(trifluoromethyl)phenyl]-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione

IUPAC name

448-trimethyl-2-[4-(trifluoromethyl)phenyl]-1H2H4H5H-[12]thiazolo[54-c]quinoline-1-thione

SMILES

CC1(C)Nc(ccc(C)c2)c2C(C2=S)=C1SN2c1ccc(C(F)(F)F)cc1

InChI

InChI=1S/C20H17F3N2S2/c1-11-4-9-15-14(10-11)16-17(19(2,3)24-15)27-25(18(16)26)13-7-5-12(6-8-13)20(21,22)23/h4-10,24H,1-3H3

InChI Key

OJBJROZAEGMSGC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01171514

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.5

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

6.299

Distribution Coefficient, logD

6.285

Water Solubility, LogSw

-5.92

Polar Surface Area

14.706

Acid Dissociation Constant (pKa)

17.92

Base Dissociation Constant (pKb)

-2.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

8009-6349 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8009-6349 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8009-6349?
Check Price and Availability of 8009-6349, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8009-6349 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8009-6349
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8009-6349
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8009-6349 available by request