8010-0260 Screening compound: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-(5-chloropyridin-2-yl)acetamide

8010-0260 Screening compound: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-(5-chloropyridin-2-yl)acetamide
8010-0260 Screening compound: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-(5-chloropyridin-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-0260
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-(5-chloropyridin-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-0260

Molecular Formula

C24H19Cl2N3O3 (C24 H19 Cl2 N3 O3)

Compound Name

2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-(5-chloropyridin-2-yl)acetamide

IUPAC name

2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-(5-chloropyridin-2-yl)acetamide

SMILES

Cc1c(CC(Nc(cc2)ncc2Cl)=O)c(cc(cc2)OC)c2n1C(c(cc1)ccc1Cl)=O

InChI

InChI=1S/C24H19Cl2N3O3/c1-14-19(12-23(30)28-22-10-7-17(26)13-27-22)20-11-18(32-2)8-9-21(20)29(14)24(31)15-3-5-16(25)6-4-15/h3-11,13H,12H2,1-2H3,(H,27,28,30)

InChI Key

FMBYXXBOTCCMFU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01899695

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.34

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.714

Distribution Coefficient, logD

5.674

Water Solubility, LogSw

-6.11

Polar Surface Area

55.504

Acid Dissociation Constant (pKa)

8.42

Base Dissociation Constant (pKb)

-0.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

8010-0260 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8010-0260 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-0260?
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What is the minimum amount of 8010-0260 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-0260
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-0260
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-0260 available by request