8010-0291 Screening compound: 3,6-bis(pyridin-4-yl)-1,2-dihydro-1,2,4,5-tetrazine

8010-0291 Screening compound: 3,6-bis(pyridin-4-yl)-1,2-dihydro-1,2,4,5-tetrazine
8010-0291 Screening compound: 3,6-bis(pyridin-4-yl)-1,2-dihydro-1,2,4,5-tetrazine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-0291
3,6-bis(pyridin-4-yl)-1,2-dihydro-1,2,4,5-tetrazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-0291

Molecular Formula

C12H10N6 (C12 H10 N6)

Compound Name

3,6-bis(pyridin-4-yl)-1,2-dihydro-1,2,4,5-tetrazine

IUPAC name

36-bis(pyridin-4-yl)-12-dihydro-1245-tetrazine

SMILES

c1cnccc1C1=NN=C(c2ccncc2)NN1

InChI

InChI=1S/C12H10N6/c1-5-13-6-2-9(1)11-15-17-12(18-16-11)10-3-7-14-8-4-10/h1-8H,(H,15,16)(H,17,18)

InChI Key

QWYDFEKBBFVMQW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00111276

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

238.25

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.504

Distribution Coefficient, logD

-1.923

Water Solubility, LogSw

-0.73

Polar Surface Area

68.517

Acid Dissociation Constant (pKa)

10.25

Base Dissociation Constant (pKb)

9.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

8010-0291 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Fragments Library (11262 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Structure:
  • Fragments
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8010-0291 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-0291?
Check Price and Availability of 8010-0291, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8010-0291 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-0291
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-0291
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-0291 available by request