8010-0767 Screening compound: ethyl 4-(4-oxo-2-phenyl-1,2,3,4-tetrahydroquinazolin-3-yl)benzoate

8010-0767 Screening compound: ethyl 4-(4-oxo-2-phenyl-1,2,3,4-tetrahydroquinazolin-3-yl)benzoate
8010-0767 Screening compound: ethyl 4-(4-oxo-2-phenyl-1,2,3,4-tetrahydroquinazolin-3-yl)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-0767
ethyl 4-(4-oxo-2-phenyl-1,2,3,4-tetrahydroquinazolin-3-yl)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-0767

Molecular Formula

C23H20N2O3 (C23 H20 N2 O3)

Compound Name

ethyl 4-(4-oxo-2-phenyl-1,2,3,4-tetrahydroquinazolin-3-yl)benzoate

IUPAC name

ethyl 4-(4-oxo-2-phenyl-1234-tetrahydroquinazolin-3-yl)benzoate

SMILES

CCOC(c(cc1)ccc1N(C(c1ccccc1)Nc1c2cccc1)C2=O)=O

InChI

InChI=1S/C23H20N2O3/c1-2-28-23(27)17-12-14-18(15-13-17)25-21(16-8-4-3-5-9-16)24-20-11-7-6-10-19(20)22(25)26/h3-15,21,24H,2H2,1H3/t21-/m0/s1

InChI Key

DKVZQCWXNJIOCS-NRFANRHFSA-N

MDL Number (MFCD)

MFCD01204802

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.930

Distribution Coefficient, logD

4.930

Water Solubility, LogSw

-4.54

Polar Surface Area

47.485

Acid Dissociation Constant (pKa)

13.92

Base Dissociation Constant (pKb)

-4.96

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.00

8010-0767 in Drug Discovery

Included in Screening Libraries

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 8010-0767 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-0767?
Check Price and Availability of 8010-0767, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8010-0767 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-0767
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-0767
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-0767 available by request