8010-1065 Screening compound: 5-[6-(5,6-dicyano-3-phenylpyrazin-2-yl)-9-oxo-9H-fluoren-3-yl]-6-phenylpyrazine-2,3-dicarbonitrile

8010-1065 Screening compound: 5-[6-(5,6-dicyano-3-phenylpyrazin-2-yl)-9-oxo-9H-fluoren-3-yl]-6-phenylpyrazine-2,3-dicarbonitrile
8010-1065 Screening compound: 5-[6-(5,6-dicyano-3-phenylpyrazin-2-yl)-9-oxo-9H-fluoren-3-yl]-6-phenylpyrazine-2,3-dicarbonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-1065
5-[6-(5,6-dicyano-3-phenylpyrazin-2-yl)-9-oxo-9H-fluoren-3-yl]-6-phenylpyrazine-2,3-dicarbonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-1065

Molecular Formula

C37H16N8O (C37 H16 N8 O)

Compound Name

5-[6-(5,6-dicyano-3-phenylpyrazin-2-yl)-9-oxo-9H-fluoren-3-yl]-6-phenylpyrazine-2,3-dicarbonitrile

IUPAC name

5-[6-(56-dicyano-3-phenylpyrazin-2-yl)-9-oxo-9H-fluoren-3-yl]-6-phenylpyrazine-23-dicarbonitrile

SMILES

N#Cc1c(C#N)nc(-c(cc2)cc(-c3c4ccc(-c5nc(C#N)c(C#N)nc5-c5ccccc5)c3)c2C4=O)c(-c2ccccc2)n1

InChI

InChI=1S/C37H16N8O/c38-17-29-31(19-40)44-35(33(42-29)21-7-3-1-4-8-21)23-11-13-25-27(15-23)28-16-24(12-14-26(28)37(25)46)36-34(22-9-5-2-6-10-22)43-30(18-39)32(20-41)45-36/h1-16H

InChI Key

VEMHNYPULKRBTE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01233426

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

588.59

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

6.828

Distribution Coefficient, logD

6.828

Water Solubility, LogSw

-6.28

Polar Surface Area

123.146

Acid Dissociation Constant (pKa)

14.00

Base Dissociation Constant (pKb)

-7.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

8010-1065 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Akt-Targeted Library (14764 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with 8010-1065 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-1065?
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What is the minimum amount of 8010-1065 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-1065
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-1065
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-1065 available by request