8010-1496 Screening compound: 2-[3,5-bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-6-bromo-4-phenylquinazoline

8010-1496 Screening compound: 2-[3,5-bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-6-bromo-4-phenylquinazoline
8010-1496 Screening compound: 2-[3,5-bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-6-bromo-4-phenylquinazoline alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-1496
2-[3,5-bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-6-bromo-4-phenylquinazoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-1496

Molecular Formula

C31H25BrN4O2 (C31 H25 BrN4 O2)

Compound Name

2-[3,5-bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-6-bromo-4-phenylquinazoline

IUPAC name

2-[35-bis(4-methoxyphenyl)-45-dihydro-1H-pyrazol-1-yl]-6-bromo-4-phenylquinazoline

SMILES

COc1ccc(C(C2)N(c3nc(-c4ccccc4)c(cc(cc4)Br)c4n3)N=C2c(cc2)ccc2OC)cc1

InChI

InChI=1S/C31H25BrN4O2/c1-37-24-13-8-20(9-14-24)28-19-29(21-10-15-25(38-2)16-11-21)36(35-28)31-33-27-17-12-23(32)18-26(27)30(34-31)22-6-4-3-5-7-22/h3-18,29H,19H2,1-2H3/t29-/m0/s1

InChI Key

IVBPBJYXWNFOJQ-LJAQVGFWSA-N

MDL Number (MFCD)

MFCD00809232

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

565.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

8.170

Distribution Coefficient, logD

8.169

Water Solubility, LogSw

-6.02

Polar Surface Area

46.718

Acid Dissociation Constant (pKa)

10.23

Base Dissociation Constant (pKb)

3.47

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.90

8010-1496 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 8010-1496 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-1496?
Check Price and Availability of 8010-1496, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8010-1496 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-1496
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-1496
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-1496 available by request