8010-3140 Screening compound: N-(5-{2-[(3-chlorophenyl)amino]-1,3-thiazol-4-yl}-4-methyl-1,3-thiazol-2-yl)benzamide

8010-3140 Screening compound: N-(5-{2-[(3-chlorophenyl)amino]-1,3-thiazol-4-yl}-4-methyl-1,3-thiazol-2-yl)benzamide
8010-3140 Screening compound: N-(5-{2-[(3-chlorophenyl)amino]-1,3-thiazol-4-yl}-4-methyl-1,3-thiazol-2-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-3140
N-(5-{2-[(3-chlorophenyl)amino]-1,3-thiazol-4-yl}-4-methyl-1,3-thiazol-2-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-3140

Molecular Formula

C20H15ClN4OS2 (C20 H15 ClN4 OS2)

Compound Name

N-(5-{2-[(3-chlorophenyl)amino]-1,3-thiazol-4-yl}-4-methyl-1,3-thiazol-2-yl)benzamide

IUPAC name

N-(5-{2-[(3-chlorophenyl)amino]-13-thiazol-4-yl}-4-methyl-13-thiazol-2-yl)benzamide

SMILES

Cc1c(-c2csc(Nc3cccc(Cl)c3)n2)sc(NC(c2ccccc2)=O)n1

InChI

InChI=1S/C20H15ClN4OS2/c1-12-17(28-20(22-12)25-18(26)13-6-3-2-4-7-13)16-11-27-19(24-16)23-15-9-5-8-14(21)10-15/h2-11H,1H3,(H,23,24)(H,22,25,26)

InChI Key

HXZDHHOYLRFCQA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01873031

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.95

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.549

Distribution Coefficient, logD

6.525

Water Solubility, LogSw

-6.22

Polar Surface Area

52.640

Acid Dissociation Constant (pKa)

8.64

Base Dissociation Constant (pKb)

2.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.00

8010-3140 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-infective Library (19449 compounds)

C-Met Library (15277 compounds)

Selective Target Activity Profiling Library (14702 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8010-3140 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-3140?
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What is the minimum amount of 8010-3140 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-3140
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-3140
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-3140 available by request