8010-4202 Screening compound: 2-(4-bromophenyl)-8-ethoxy-4,4-dimethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione

8010-4202 Screening compound: 2-(4-bromophenyl)-8-ethoxy-4,4-dimethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione
8010-4202 Screening compound: 2-(4-bromophenyl)-8-ethoxy-4,4-dimethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-4202
2-(4-bromophenyl)-8-ethoxy-4,4-dimethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-4202

Molecular Formula

C20H19BrN2OS2 (C20 H19 BrN2 OS2)

Compound Name

2-(4-bromophenyl)-8-ethoxy-4,4-dimethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione

IUPAC name

2-(4-bromophenyl)-8-ethoxy-44-dimethyl-1H2H4H5H-[12]thiazolo[54-c]quinoline-1-thione

SMILES

CCOc(cc1)cc2c1NC(C)(C)C(SN1c(cc3)ccc3Br)=C2C1=S

InChI

InChI=1S/C20H19BrN2OS2/c1-4-24-14-9-10-16-15(11-14)17-18(20(2,3)22-16)26-23(19(17)25)13-7-5-12(21)6-8-13/h5-11,22H,4H2,1-3H3

InChI Key

AORRBAZEIYMYHM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01872420

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.356

Distribution Coefficient, logD

6.128

Water Solubility, LogSw

-5.71

Polar Surface Area

21.829

Acid Dissociation Constant (pKa)

17.72

Base Dissociation Constant (pKb)

-2.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

8010-4202 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with 8010-4202 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-4202?
Check Price and Availability of 8010-4202, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8010-4202 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-4202
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-4202
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-4202 available by request