8010-6241 Screening compound: 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-(2,4-dimethoxyphenyl)-1,3-thiazole

8010-6241 Screening compound: 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-(2,4-dimethoxyphenyl)-1,3-thiazole
8010-6241 Screening compound: 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-(2,4-dimethoxyphenyl)-1,3-thiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound 8010-6241
2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-(2,4-dimethoxyphenyl)-1,3-thiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8010-6241

Molecular Formula

C19H17NO4S (C19 H17 NO4 S)

Compound Name

2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-(2,4-dimethoxyphenyl)-1,3-thiazole

IUPAC name

2-(23-dihydro-14-benzodioxin-2-yl)-4-(24-dimethoxyphenyl)-13-thiazole

SMILES

COc(cc1)cc(OC)c1-c1csc(C2Oc(cccc3)c3OC2)n1

InChI

InChI=1S/C19H17NO4S/c1-21-12-7-8-13(17(9-12)22-2)14-11-25-19(20-14)18-10-23-15-5-3-4-6-16(15)24-18/h3-9,11,18H,10H2,1-2H3/t18-/m0/s1

InChI Key

OAQCGPJPQWZSJP-SFHVURJKSA-N

MDL Number (MFCD)

MFCD02049278

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

355.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.381

Distribution Coefficient, logD

4.381

Water Solubility, LogSw

-4.52

Polar Surface Area

40.312

Acid Dissociation Constant (pKa)

30.14

Base Dissociation Constant (pKb)

-1.84

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

21.10

8010-6241 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Receptor-type Protein Tyrosine Phosphatases Library (3746 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Nervous system
  • Female
  • Metabolic
  • Endocrine
Targets:
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8010-6241 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8010-6241?
Check Price and Availability of 8010-6241, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8010-6241 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8010-6241
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8010-6241
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8010-6241 available by request