8011-1858 Screening compound: 6,7-dimethoxy-3,3,3',3'-tetramethyl-3H,3'H,4H,4'H-1,1'-biisoquinoline

8011-1858 Screening compound: 6,7-dimethoxy-3,3,3',3'-tetramethyl-3H,3'H,4H,4'H-1,1'-biisoquinoline
8011-1858 Screening compound: 6,7-dimethoxy-3,3,3',3'-tetramethyl-3H,3'H,4H,4'H-1,1'-biisoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound 8011-1858
6,7-dimethoxy-3,3,3',3'-tetramethyl-3H,3'H,4H,4'H-1,1'-biisoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8011-1858

Molecular Formula

C24H28N2O2 (C24 H28 N2 O2)

Compound Name

6,7-dimethoxy-3,3,3',3'-tetramethyl-3H,3'H,4H,4'H-1,1'-biisoquinoline

IUPAC name

67-dimethoxy-333'3'-tetramethyl-3H3'H4H4'H-11'-biisoquinoline

SMILES

CC(C)(Cc1c2cccc1)N=C2C(c1c2)=NC(C)(C)Cc1cc(OC)c2OC

InChI

InChI=1S/C24H28N2O2/c1-23(2)13-15-9-7-8-10-17(15)21(25-23)22-18-12-20(28-6)19(27-5)11-16(18)14-24(3,4)26-22/h7-12H,13-14H2,1-6H3

InChI Key

TUDDBIBRAYSSQV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02648128

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.370

Distribution Coefficient, logD

4.344

Water Solubility, LogSw

-4.53

Polar Surface Area

30.972

Acid Dissociation Constant (pKa)

25.98

Base Dissociation Constant (pKb)

6.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.67

8011-1858 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with 8011-1858 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8011-1858?
Check Price and Availability of 8011-1858, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8011-1858 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8011-1858
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8011-1858
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8011-1858 available by request