8011-4949 Screening compound: 2,2-diethyl-3-phenyl-2,3-dihydro-4(1H)-quinazolinone

8011-4949 Screening compound: 2,2-diethyl-3-phenyl-2,3-dihydro-4(1H)-quinazolinone
8011-4949 Screening compound: 2,2-diethyl-3-phenyl-2,3-dihydro-4(1H)-quinazolinone alternative view

Chemical Structure Depiction of ChemDiv screening compound 8011-4949
2,2-diethyl-3-phenyl-2,3-dihydro-4(1H)-quinazolinone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8011-4949

Molecular Formula

C18H20N2O (C18 H20 N2 O)

Compound Name

2,2-diethyl-3-phenyl-2,3-dihydro-4(1H)-quinazolinone

IUPAC name

22-diethyl-3-phenyl-1234-tetrahydroquinazolin-4-one

SMILES

CCC(CC)(Nc1c2cccc1)N(c1ccccc1)C2=O

InChI

InChI=1S/C18H20N2O/c1-3-18(4-2)19-16-13-9-8-12-15(16)17(21)20(18)14-10-6-5-7-11-14/h5-13,19H,3-4H2,1-2H3

InChI Key

OWQVYBRVADYDGU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02029541

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

280.37

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.025

Distribution Coefficient, logD

4.025

Water Solubility, LogSw

-4.19

Polar Surface Area

27.653

Acid Dissociation Constant (pKa)

16.80

Base Dissociation Constant (pKb)

-0.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.78

8011-4949 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8011-4949 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8011-4949?
Check Price and Availability of 8011-4949, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8011-4949 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8011-4949
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8011-4949
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8011-4949 available by request