8011-9718 Screening compound: 4-hydroxy-3-[2-(4-hydroxy-4,7,7,9,9-pentamethyl-2-oxo-1-oxa-3,8-diazaspiro[4.5]dec-3-yl)ethyl]-4,7,7,9,9-pentamethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one

8011-9718 Screening compound: 4-hydroxy-3-[2-(4-hydroxy-4,7,7,9,9-pentamethyl-2-oxo-1-oxa-3,8-diazaspiro[4.5]dec-3-yl)ethyl]-4,7,7,9,9-pentamethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
8011-9718 Screening compound: 4-hydroxy-3-[2-(4-hydroxy-4,7,7,9,9-pentamethyl-2-oxo-1-oxa-3,8-diazaspiro[4.5]dec-3-yl)ethyl]-4,7,7,9,9-pentamethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8011-9718
4-hydroxy-3-[2-(4-hydroxy-4,7,7,9,9-pentamethyl-2-oxo-1-oxa-3,8-diazaspiro[4.5]dec-3-yl)ethyl]-4,7,7,9,9-pentamethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8011-9718

Molecular Formula

C26H46N4O6 (C26 H46 N4 O6)

Compound Name

4-hydroxy-3-[2-(4-hydroxy-4,7,7,9,9-pentamethyl-2-oxo-1-oxa-3,8-diazaspiro[4.5]dec-3-yl)ethyl]-4,7,7,9,9-pentamethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one

IUPAC name

4-hydroxy-3-(2-{4-hydroxy-47799-pentamethyl-2-oxo-1-oxa-38-diazaspiro[4.5]decan-3-yl}ethyl)-47799-pentamethyl-1-oxa-38-diazaspiro[4.5]decan-2-one

SMILES

CC(C1(CC(C)(C)NC(C)(C)C1)O1)(N(CCN(C(C)(C2(CC(C)(C)NC(C)(C)C2)O2)O)C2=O)C1=O)O

InChI

InChI=1S/C26H46N4O6/c1-19(2)13-25(14-20(3,4)27-19)23(9,33)29(17(31)35-25)11-12-30-18(32)36-26(24(30,10)34)15-21(5,6)28-22(7,8)16-26/h27-28,33-34H,11-16H2,1-10H3

InChI Key

WXAHUZVBJCOTTE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02933463

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

510.67

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.854

Distribution Coefficient, logD

-0.891

Water Solubility, LogSw

-3.05

Polar Surface Area

100.490

Acid Dissociation Constant (pKa)

15.67

Base Dissociation Constant (pKb)

11.14

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

92.31

8011-9718 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8011-9718 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8011-9718?
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What is the minimum amount of 8011-9718 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8011-9718
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8011-9718
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8011-9718 available by request