8012-0074 Screening compound: 5,7-dimethyl-N-propyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide

8012-0074 Screening compound: 5,7-dimethyl-N-propyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide
8012-0074 Screening compound: 5,7-dimethyl-N-propyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8012-0074
5,7-dimethyl-N-propyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8012-0074

Molecular Formula

C10H15N5O2S (C10 H15 N5 O2 S)

Compound Name

5,7-dimethyl-N-propyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide

IUPAC name

57-dimethyl-N-propyl-[124]triazolo[15-a]pyrimidine-2-sulfonamide

SMILES

CCCNS(c1nn2c(C)cc(C)nc2n1)(=O)=O

InChI

InChI=1S/C10H15N5O2S/c1-4-5-11-18(16,17)10-13-9-12-7(2)6-8(3)15(9)14-10/h6,11H,4-5H2,1-3H3

InChI Key

NDIJGNIAWORYAR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02933591

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

269.33

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.772

Distribution Coefficient, logD

0.755

Water Solubility, LogSw

-1.97

Polar Surface Area

72.251

Acid Dissociation Constant (pKa)

8.82

Base Dissociation Constant (pKb)

1.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

8012-0074 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Fragments Library (11262 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Structure:
  • Fragments
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8012-0074 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8012-0074?
Check Price and Availability of 8012-0074, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8012-0074 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8012-0074
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8012-0074
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8012-0074 available by request