8015-1102 Screening compound: 3-[4-(4-methylphenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-[4-(trifluoromethoxy)phenyl]propanamide

8015-1102 Screening compound: 3-[4-(4-methylphenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-[4-(trifluoromethoxy)phenyl]propanamide
8015-1102 Screening compound: 3-[4-(4-methylphenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-[4-(trifluoromethoxy)phenyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8015-1102
3-[4-(4-methylphenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-[4-(trifluoromethoxy)phenyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8015-1102

Molecular Formula

C25H20F3N3O3 (C25 H20 F3 N3 O3)

Compound Name

3-[4-(4-methylphenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-[4-(trifluoromethoxy)phenyl]propanamide

IUPAC name

3-[4-(4-methylphenyl)-1-oxo-12-dihydrophthalazin-2-yl]-N-[4-(trifluoromethoxy)phenyl]propanamide

SMILES

Cc(cc1)ccc1C(c1c2cccc1)=NN(CCC(Nc(cc1)ccc1OC(F)(F)F)=O)C2=O

InChI

InChI=1S/C25H20F3N3O3/c1-16-6-8-17(9-7-16)23-20-4-2-3-5-21(20)24(33)31(30-23)15-14-22(32)29-18-10-12-19(13-11-18)34-25(26,27)28/h2-13H,14-15H2,1H3,(H,29,32)

InChI Key

ZOXKWLOCMOXFNO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03855582

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.162

Distribution Coefficient, logD

5.162

Water Solubility, LogSw

-4.96

Polar Surface Area

56.260

Acid Dissociation Constant (pKa)

12.13

Base Dissociation Constant (pKb)

4.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

8015-1102 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8015-1102 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8015-1102?
Check Price and Availability of 8015-1102, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8015-1102 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8015-1102
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8015-1102
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8015-1102 available by request