8015-1378 Screening compound: 3-({[1,1'-biphenyl]-4-yl}formamido)-3-(4-ethoxyphenyl)propanoic acid

8015-1378 Screening compound: 3-({[1,1'-biphenyl]-4-yl}formamido)-3-(4-ethoxyphenyl)propanoic acid
8015-1378 Screening compound: 3-({[1,1'-biphenyl]-4-yl}formamido)-3-(4-ethoxyphenyl)propanoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound 8015-1378
3-({[1,1'-biphenyl]-4-yl}formamido)-3-(4-ethoxyphenyl)propanoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8015-1378

Molecular Formula

C24H23NO4 (C24 H23 NO4)

Compound Name

3-({[1,1'-biphenyl]-4-yl}formamido)-3-(4-ethoxyphenyl)propanoic acid

IUPAC name

3-({[11'-biphenyl]-4-yl}formamido)-3-(4-ethoxyphenyl)propanoic acid

SMILES

CCOc1ccc(C(CC(O)=O)NC(c(cc2)ccc2-c2ccccc2)=O)cc1

InChI

InChI=1S/C24H23NO4/c1-2-29-21-14-12-19(13-15-21)22(16-23(26)27)25-24(28)20-10-8-18(9-11-20)17-6-4-3-5-7-17/h3-15,22H,2,16H2,1H3,(H,25,28)(H,26,27)/t22-/m0/s1

InChI Key

RFRYYVRXLSTESC-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD03855812

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.388

Distribution Coefficient, logD

1.750

Water Solubility, LogSw

-4.29

Polar Surface Area

59.518

Acid Dissociation Constant (pKa)

4.76

Base Dissociation Constant (pKb)

-5.50

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.70

8015-1378 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

Glucocorticoid receptors Library (4806 compounds)

Integrin Receptors Targeted library (1715 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Nuclear receptors
  • Others
  • Nuclear receptors
  • Phosphatases
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with 8015-1378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8015-1378?
Check Price and Availability of 8015-1378, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8015-1378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8015-1378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8015-1378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8015-1378 available by request