8015-7066 Screening compound: 6-chloro-3-[(1-methyl-1H-imidazol-2-yl)sulfanyl]-4-phenyl-1,2-dihydroquinolin-2-one

8015-7066 Screening compound: 6-chloro-3-[(1-methyl-1H-imidazol-2-yl)sulfanyl]-4-phenyl-1,2-dihydroquinolin-2-one
8015-7066 Screening compound: 6-chloro-3-[(1-methyl-1H-imidazol-2-yl)sulfanyl]-4-phenyl-1,2-dihydroquinolin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8015-7066
6-chloro-3-[(1-methyl-1H-imidazol-2-yl)sulfanyl]-4-phenyl-1,2-dihydroquinolin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8015-7066

Molecular Formula

C19H14ClN3OS (C19 H14 ClN3 OS)

Compound Name

6-chloro-3-[(1-methyl-1H-imidazol-2-yl)sulfanyl]-4-phenyl-1,2-dihydroquinolin-2-one

IUPAC name

6-chloro-3-[(1-methyl-1H-imidazol-2-yl)sulfanyl]-4-phenyl-12-dihydroquinolin-2-one

SMILES

Cn1c(SC2=C(c3ccccc3)c(cc(cc3)Cl)c3NC2=O)ncc1

InChI

InChI=1S/C19H14ClN3OS/c1-23-10-9-21-19(23)25-17-16(12-5-3-2-4-6-12)14-11-13(20)7-8-15(14)22-18(17)24/h2-11H,1H3,(H,22,24)

InChI Key

CZYYFUXPXVBTSM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04056203

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

367.86

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.118

Distribution Coefficient, logD

4.118

Water Solubility, LogSw

-4.56

Polar Surface Area

37.492

Acid Dissociation Constant (pKa)

11.39

Base Dissociation Constant (pKb)

1.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

8015-7066 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

BRD4 Targeted Library (4534 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Others
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8015-7066 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8015-7066?
Check Price and Availability of 8015-7066, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8015-7066 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8015-7066
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8015-7066
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8015-7066 available by request