8015-8749 Screening compound: 4-methyl-5-(2-{[3-(trifluoromethyl)phenyl]amino}-1,3-thiazol-4-yl)-1,3-thiazol-2-amine

8015-8749 Screening compound: 4-methyl-5-(2-{[3-(trifluoromethyl)phenyl]amino}-1,3-thiazol-4-yl)-1,3-thiazol-2-amine
8015-8749 Screening compound: 4-methyl-5-(2-{[3-(trifluoromethyl)phenyl]amino}-1,3-thiazol-4-yl)-1,3-thiazol-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8015-8749
4-methyl-5-(2-{[3-(trifluoromethyl)phenyl]amino}-1,3-thiazol-4-yl)-1,3-thiazol-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8015-8749

Molecular Formula

C14H11F3N4S2 (C14 H11 F3 N4 S2)

Compound Name

4-methyl-5-(2-{[3-(trifluoromethyl)phenyl]amino}-1,3-thiazol-4-yl)-1,3-thiazol-2-amine

IUPAC name

4-methyl-5-(2-{[3-(trifluoromethyl)phenyl]amino}-13-thiazol-4-yl)-13-thiazol-2-amine

SMILES

Cc1c(-c2csc(Nc3cc(C(F)(F)F)ccc3)n2)sc(N)n1

InChI

InChI=1S/C14H11F3N4S2/c1-7-11(23-12(18)19-7)10-6-22-13(21-10)20-9-4-2-3-8(5-9)14(15,16)17/h2-6H,1H3,(H2,18,19)(H,20,21)

InChI Key

VMVYNWWVDJTLKX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05258870

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.4

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.243

Distribution Coefficient, logD

5.148

Water Solubility, LogSw

-5.34

Polar Surface Area

50.306

Acid Dissociation Constant (pKa)

18.69

Base Dissociation Constant (pKb)

6.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

8015-8749 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8015-8749 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8015-8749?
Check Price and Availability of 8015-8749, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8015-8749 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8015-8749
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8015-8749
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8015-8749 available by request