8017-2391 Screening compound: N-(2-benzoyl-4-chlorophenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]acetamide

8017-2391 Screening compound: N-(2-benzoyl-4-chlorophenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]acetamide
8017-2391 Screening compound: N-(2-benzoyl-4-chlorophenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8017-2391
N-(2-benzoyl-4-chlorophenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8017-2391

Molecular Formula

C24H23ClN4O2 (C24 H23 ClN4 O2)

Compound Name

N-(2-benzoyl-4-chlorophenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]acetamide

IUPAC name

N-(2-benzoyl-4-chlorophenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]acetamide

SMILES

O=C(CN(CC1)CCN1c1ncccc1)Nc(ccc(Cl)c1)c1C(c1ccccc1)=O

InChI

InChI=1S/C24H23ClN4O2/c25-19-9-10-21(20(16-19)24(31)18-6-2-1-3-7-18)27-23(30)17-28-12-14-29(15-13-28)22-8-4-5-11-26-22/h1-11,16H,12-15,17H2,(H,27,30)

InChI Key

WVEKIBXWYPCCJL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06015198

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.93

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.596

Distribution Coefficient, logD

4.569

Water Solubility, LogSw

-4.72

Polar Surface Area

51.661

Acid Dissociation Constant (pKa)

9.17

Base Dissociation Constant (pKb)

6.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.83

8017-2391 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

MCL1 Targeted Library (12200 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with 8017-2391 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8017-2391?
Check Price and Availability of 8017-2391, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8017-2391 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8017-2391
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8017-2391
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8017-2391 available by request