8017-4380 Screening compound: N-(5-fluoro-4-morpholino-2-pyrimidinyl)-N-(4-methoxyphenyl)amine

8017-4380 Screening compound: N-(5-fluoro-4-morpholino-2-pyrimidinyl)-N-(4-methoxyphenyl)amine
8017-4380 Screening compound: N-(5-fluoro-4-morpholino-2-pyrimidinyl)-N-(4-methoxyphenyl)amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8017-4380
N-(5-fluoro-4-morpholino-2-pyrimidinyl)-N-(4-methoxyphenyl)amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8017-4380

Molecular Formula

C15H17FN4O2 (C15 H17 FN4 O2)

Compound Name

N-(5-fluoro-4-morpholino-2-pyrimidinyl)-N-(4-methoxyphenyl)amine

IUPAC name

5-fluoro-N-(4-methoxyphenyl)-4-(morpholin-4-yl)pyrimidin-2-amine

SMILES

COc(cc1)ccc1Nc(nc1)nc(N2CCOCC2)c1F

InChI

InChI=1S/C15H17FN4O2/c1-21-12-4-2-11(3-5-12)18-15-17-10-13(16)14(19-15)20-6-8-22-9-7-20/h2-5,10H,6-9H2,1H3,(H,17,18,19)

InChI Key

ZAKWOXFASIIAJK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03547002

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

304.32

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.898

Distribution Coefficient, logD

2.898

Water Solubility, LogSw

-3.29

Polar Surface Area

48.216

Acid Dissociation Constant (pKa)

16.07

Base Dissociation Constant (pKb)

3.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.33

8017-4380 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Human Receptors Annotated Library (5376 compounds)

Akt-Targeted Library (14764 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with 8017-4380 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8017-4380?
Check Price and Availability of 8017-4380, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8017-4380 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8017-4380
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8017-4380
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8017-4380 available by request