8018-1206 Screening compound: 1-{6-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl}-4-(pyridin-2-yl)piperazine

8018-1206 Screening compound: 1-{6-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl}-4-(pyridin-2-yl)piperazine
8018-1206 Screening compound: 1-{6-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl}-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-1206
1-{6-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl}-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-1206

Molecular Formula

C15H17N7 (C15 H17 N7)

Compound Name

1-{6-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl}-4-(pyridin-2-yl)piperazine

IUPAC name

1-{6-methyl-[124]triazolo[43-b]pyridazin-8-yl}-4-(pyridin-2-yl)piperazine

SMILES

Cc(cc1N(CC2)CCN2c2ncccc2)nn2c1nnc2

InChI

InChI=1S/C15H17N7/c1-12-10-13(15-18-17-11-22(15)19-12)20-6-8-21(9-7-20)14-4-2-3-5-16-14/h2-5,10-11H,6-9H2,1H3

InChI Key

CGPXLDORNYGGON-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07022744

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

295.35

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.230

Distribution Coefficient, logD

1.223

Water Solubility, LogSw

-0.87

Polar Surface Area

48.596

Acid Dissociation Constant (pKa)

24.46

Base Dissociation Constant (pKb)

5.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.33

8018-1206 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Fragments Library (11262 compounds)

GPCR Targeted Library (31838 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Structure:
  • Fragments
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with 8018-1206 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-1206?
Check Price and Availability of 8018-1206, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8018-1206 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-1206
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-1206
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-1206 available by request