8018-2126 Screening compound: 4,8-dimethyl-6-[(4-phenylpiperazino)sulfonyl]-2(1H)-quinolinone

8018-2126 Screening compound: 4,8-dimethyl-6-[(4-phenylpiperazino)sulfonyl]-2(1H)-quinolinone
8018-2126 Screening compound: 4,8-dimethyl-6-[(4-phenylpiperazino)sulfonyl]-2(1H)-quinolinone alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-2126
4,8-dimethyl-6-[(4-phenylpiperazino)sulfonyl]-2(1H)-quinolinone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-2126

Molecular Formula

C21H23N3O3S (C21 H23 N3 O3 S)

Compound Name

4,8-dimethyl-6-[(4-phenylpiperazino)sulfonyl]-2(1H)-quinolinone

IUPAC name

48-dimethyl-6-[(4-phenylpiperazin-1-yl)sulfonyl]-12-dihydroquinolin-2-one

SMILES

Cc1cc(S(N(CC2)CCN2c2ccccc2)(=O)=O)cc(C(C)=C2)c1NC2=O

InChI

InChI=1S/C21H23N3O3S/c1-15-13-20(25)22-21-16(2)12-18(14-19(15)21)28(26,27)24-10-8-23(9-11-24)17-6-4-3-5-7-17/h3-7,12-14H,8-11H2,1-2H3,(H,22,25)

InChI Key

RRLJDYZJUNOATK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07657330

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.802

Distribution Coefficient, logD

2.766

Water Solubility, LogSw

-3.49

Polar Surface Area

57.778

Acid Dissociation Constant (pKa)

8.46

Base Dissociation Constant (pKb)

2.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.57

8018-2126 in Drug Discovery

Included in Screening Libraries

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with 8018-2126 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-2126?
Check Price and Availability of 8018-2126, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8018-2126 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-2126
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-2126
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-2126 available by request