8018-2537 Screening compound: 5-bromo-3-hydroxy-3-[2-methoxy-6-(trifluoromethyl)phenyl]-1,3-dihydro-2H-indol-2-one

8018-2537 Screening compound: 5-bromo-3-hydroxy-3-[2-methoxy-6-(trifluoromethyl)phenyl]-1,3-dihydro-2H-indol-2-one
8018-2537 Screening compound: 5-bromo-3-hydroxy-3-[2-methoxy-6-(trifluoromethyl)phenyl]-1,3-dihydro-2H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-2537
5-bromo-3-hydroxy-3-[2-methoxy-6-(trifluoromethyl)phenyl]-1,3-dihydro-2H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-2537

Molecular Formula

C16H11BrF3NO3 (C16 H11 BrF3 NO3)

Compound Name

5-bromo-3-hydroxy-3-[2-methoxy-6-(trifluoromethyl)phenyl]-1,3-dihydro-2H-indol-2-one

IUPAC name

n/a

SMILES

COc1c(C(c(cc(cc2)Br)c2N2)(C2=O)O)c(C(F)(F)F)ccc1

InChI

InChI=1S/C16H11BrF3NO3/c1-24-12-4-2-3-9(16(18,19)20)13(12)15(23)10-7-8(17)5-6-11(10)21-14(15)22/h2-7,23H,1H3,(H,21,22)/t15-/m1/s1

InChI Key

XQMJNTHNLNQZBV-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD07657651

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.17

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.659

Distribution Coefficient, logD

3.645

Water Solubility, LogSw

-4.16

Polar Surface Area

47.734

Acid Dissociation Constant (pKa)

8.90

Base Dissociation Constant (pKb)

-1.79

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

18.80

8018-2537 in Drug Discovery

Included in Screening Libraries

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with 8018-2537 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-2537?
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What is the minimum amount of 8018-2537 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-2537
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-2537
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-2537 available by request