8018-3108 Screening compound: 5-(2-chlorophenyl)-7-methoxy-3-phenyl-2H,3H-[1,3]thiazolo[4,5-d]pyrimidine-2-thione

8018-3108 Screening compound: 5-(2-chlorophenyl)-7-methoxy-3-phenyl-2H,3H-[1,3]thiazolo[4,5-d]pyrimidine-2-thione
8018-3108 Screening compound: 5-(2-chlorophenyl)-7-methoxy-3-phenyl-2H,3H-[1,3]thiazolo[4,5-d]pyrimidine-2-thione alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-3108
5-(2-chlorophenyl)-7-methoxy-3-phenyl-2H,3H-[1,3]thiazolo[4,5-d]pyrimidine-2-thione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-3108

Molecular Formula

C18H12ClN3OS2 (C18 H12 ClN3 OS2)

Compound Name

5-(2-chlorophenyl)-7-methoxy-3-phenyl-2H,3H-[1,3]thiazolo[4,5-d]pyrimidine-2-thione

IUPAC name

5-(2-chlorophenyl)-7-methoxy-3-phenyl-2H3H-[13]thiazolo[45-d]pyrimidine-2-thione

SMILES

COc(nc(-c(cccc1)c1Cl)nc1N2c3ccccc3)c1SC2=S

InChI

InChI=1S/C18H12ClN3OS2/c1-23-17-14-16(20-15(21-17)12-9-5-6-10-13(12)19)22(18(24)25-14)11-7-3-2-4-8-11/h2-10H,1H3

InChI Key

PXDWHBMRUQVFSI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07657865

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.9

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.090

Distribution Coefficient, logD

5.090

Water Solubility, LogSw

-5.34

Polar Surface Area

29.931

Acid Dissociation Constant (pKa)

28.13

Base Dissociation Constant (pKb)

-0.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

8018-3108 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8018-3108 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-3108?
Check Price and Availability of 8018-3108, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8018-3108 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-3108
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-3108
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-3108 available by request